Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables ubiquitin protein ligase activity. Acts upstream of or within several processes, including forelimb morphogenesis; nervous system development; and positive regulation of BMP signaling pathway. Located in nucleus. Part of protein-containing complex. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human ARK2C (arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C).