Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables 3',5'-cyclic-AMP phosphodiesterase activity. Acts upstream of or within several processes, including behavioral fear response; learning; and negative regulation of steroid hormone biosynthetic process. Predicted to be active in cytosol; nucleus; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; hindlimb digit; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE8B (phosphodiesterase 8B).