Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables endopeptidase activator activity and enzyme binding activity. Acts upstream of or within Notch receptor processing and metanephros development. Predicted to be located in Golgi apparatus; cytoplasmic vesicle; and synaptic membrane. Predicted to be part of gamma-secretase complex. Predicted to be active in endoplasmic reticulum and presynaptic membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system; and retina. Orthologous to human APH1A (aph-1 homolog A, gamma-secretase subunit).