Automated description from the Alliance of Genome Resources (Release 8.3.0)
Enables protein homodimerization activity. Involved in heterophilic cell-cell adhesion and homophilic cell-cell adhesion. Acts upstream of or within intracellular protein localization. Located in cell-cell junction. Is active in parallel fiber to Purkinje cell synapse and presynaptic membrane. Is expressed in several structures, including intestine; liver; nervous system; neural retina; and olfactory epithelium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3).
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