Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables double-stranded RNA binding activity and left-handed Z-DNA binding activity. Involved in several processes, including defense response to other organism; positive regulation of defense response; and positive regulation of programmed cell death. Acts upstream of or within positive regulation of type I interferon-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in eye and heart. Orthologous to human ZBP1 (Z-DNA binding protein 1).