Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable 2 iron, 2 sulfur cluster binding activity and protein homodimerization activity. Predicted to be involved in regulation of autophagy. Predicted to act upstream of or within autophagy. Located in endoplasmic reticulum membrane and mitochondrial outer membrane. Is expressed in central nervous system and retina. Used to study Wolfram syndrome 2. Human ortholog(s) of this gene implicated in Wolfram syndrome 2. Orthologous to human CISD2 (CDGSH iron sulfur domain 2).