Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including GTPase activator activity; SH2 domain binding activity; and phospholipase binding activity. Acts upstream of or within several processes, including actin cytoskeleton organization; focal adhesion assembly; and nervous system development. Predicted to be located in several cellular components, including caveola; cortical actin cytoskeleton; and ruffle membrane. Predicted to be active in focal adhesion and membrane raft. Predicted to colocalize with actin filament and stress fiber. Is expressed in several structures, including alimentary system; central nervous system; heart; hemolymphoid system gland; and placenta. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human DLC1 (DLC1 Rho GTPase activating protein).