Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and lipopolysaccharide binding activity. Involved in several processes, including cellular response to corticotropin-releasing hormone stimulus; detection of lipopolysaccharide; and non-canonical inflammasome complex assembly. Acts upstream of or within several processes, including positive regulation of apoptotic process; positive regulation of transcription by RNA polymerase II; and skeletal muscle cell differentiation. Located in cytosol and nucleus. Part of chromatin and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and peripheral nervous system. Orthologous to human NR4A1 (nuclear receptor subfamily 4 group A member 1).