Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 9.0.0)

Predicted to enable several functions, including BAT3 complex binding activity; ubiquitin-specific protease binding activity; and ubiquitin-ubiquitin ligase activity. Involved in negative regulation of canonical Wnt signaling pathway and regulation of SREBP signaling pathway. Predicted to be located in several cellular components, including growth cone; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of ATPase complex; Derlin-1 retrotranslocation complex; and ubiquitin ligase complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including central nervous system; genitourinary system; integumental system; liver; and retina nuclear layer. Used to study metabolic dysfunction-associated steatohepatitis. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 89. Orthologous to human AMFR (autocrine motility factor receptor).

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Gene Ontology Evidence Code Abbreviations:

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