Automated description from the Alliance of Genome Resources (Release 5.4.0)
Enables several functions, including cAMP-dependent protein kinase inhibitor activity; calcium- and calmodulin-responsive adenylate cyclase activity; and molecular function inhibitor activity. Involved in several processes, including cellular response to organonitrogen compound; positive regulation of CREB transcription factor activity; and regulation of synaptic plasticity. Acts upstream of or within long-term memory. Located in several cellular components, including basolateral plasma membrane; neuronal cell body membrane; and postsynaptic density. Is active in several cellular components, including Schaffer collateral - CA1 synapse; hippocampal mossy fiber to CA3 synapse; and presynaptic membrane. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and sensory organ. Orthologous to human ADCY8 (adenylate cyclase 8).