Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables metalloendopeptidase activity. Involved in several processes, including bone mineralization; endochondral ossification; and extracellular matrix disassembly. Acts upstream of or within collagen catabolic process; growth plate cartilage development; and protein metabolic process. Predicted to be located in intercellular canaliculus. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; connective tissue; inner ear; limb; and skeletal system. Human ortholog(s) of this gene implicated in anodontia; artery disease (multiple); bone disease (multiple); and ovarian carcinoma. Orthologous to human MMP13 (matrix metallopeptidase 13).