Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables Wnt-protein binding activity. Involved in negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway and regulation of presynapse assembly. Acts upstream of or within several processes, including Wnt signaling pathway; heart morphogenesis; and negative regulation of signal transduction. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Orthologous to human FZD1 (frizzled class receptor 1).