Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables type I interferon receptor activity. Acts upstream of or within immature T cell proliferation in thymus and regulation of transcription by RNA polymerase II. Located in extracellular space. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; liver; and nervous system. Human ortholog(s) of this gene implicated in hepatitis B and immunodeficiency 45. Orthologous to human IFNAR2 (interferon alpha and beta receptor subunit 2).