Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable several functions, including D2 dopamine receptor binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within aorta development; coronary vasculature development; and ventricular septum development. Located in clathrin-coated pit; photoreceptor inner segment; and presynapse. Is expressed in several structures, including alimentary system; central nervous system; oocyte; sensory organ; and skin. Used to study centronuclear myopathy; cystic kidney disease; microcytic anemia; and myopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (dynamin 2).