Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables protein domain specific binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; synaptic target recognition; and tube morphogenesis. Acts upstream of or within ERK1 and ERK2 cascade; protein targeting; and regulation of programmed cell death. Located in nucleus. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Used to study schizophrenia. Orthologous to human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta).