Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables Wnt-protein binding activity. Involved in camera-type eye development; canonical Wnt signaling pathway; and positive regulation of cytokine production. Acts upstream of or within several processes, including chorionic trophoblast cell differentiation; columnar/cuboidal epithelial cell maturation; and embryonic organ development. Located in several cellular components, including Golgi apparatus; bicellular tight junction; and perinuclear region of cytoplasm. Colocalizes with early endosome. Is expressed in several structures, including alimentary system; early conceptus; embryo ectoderm; genitourinary system; and sensory organ. Orthologous to human FZD5 (frizzled class receptor 5).