Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables Wnt-protein binding activity; endopeptidase activator activity; and receptor ligand activity. Involved in several processes, including regulation of gene expression; regulation of protein phosphorylation; and regulation of signal transduction. Acts upstream of or within several processes, including Wnt signaling pathway; collagen fibril organization; and negative regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human SFRP2 (secreted frizzled related protein 2).