Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables several functions, including disordered domain specific binding activity; protein homodimerization activity; and zinc ion binding activity. Involved in canonical Wnt signaling pathway and proteasome-mediated ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including male meiosis I; regulation of growth; and spermatogenesis. Part of SCF ubiquitin ligase complex. Is expressed in several structures, including alimentary system; early embryo; gonad; hemolymphoid system gland; and liver. Orthologous to human SIAH1 (siah E3 ubiquitin protein ligase 1).