Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables RNA binding activity; promoter-specific chromatin binding activity; and transcription coregulator activity. Involved in several processes, including RNA metabolic process; regulation of alternative mRNA splicing, via spliceosome; and regulation of osteoblast differentiation. Acts upstream of or within circadian rhythm; positive regulation of DNA-templated transcription; and protein import into nucleus. Predicted to be located in nuclear speck and nucleolus. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human DDX5 (DEAD-box helicase 5).