Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables non-membrane spanning protein tyrosine kinase activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of cell migration; and regulation of organelle organization. Acts upstream of with a positive effect on positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within cellular response to fluid shear stress. Located in nucleus and perinuclear region of cytoplasm. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and presynapse. Is expressed in several structures, including blastocyst; early embryo; gonad; gonad primordium; and liver. Human ortholog(s) of this gene implicated in breast cancer and hypertension. Orthologous to human PTK2B (protein tyrosine kinase 2 beta).