Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables SH3 domain binding activity. Involved in several processes, including positive regulation of myeloid leukocyte differentiation; positive regulation of tyrosine phosphorylation of STAT protein; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in thymus primordium. Orthologous to human HCLS1 (hematopoietic cell-specific Lyn substrate 1).