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Symbol
Name
ID

Irs1
insulin receptor substrate 1
MGI:99454

Phenotype annotations related to mortality/aging

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Sudden cardiac death
Disease(s) Associated with IRS1	Sudden cardiac death
coronary artery disease

Mouse Phenotypes		mortality/aging	premature death	postnatal lethality	preweaning lethality, complete penetrance
Availability	Mouse Genotype	mortality/aging	premature death	postnatal lethality	preweaning lethality, complete penetrance
	Irs1^em1(IMPC)H/Irs1^em1(IMPC)H
	Irs1^smla/Irs1^smla	*!		!

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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