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Symbol
Name
ID

Tyr
tyrosinase
MGI:98880

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes

Astigmatism

Blue irides

Ocular albinism

Hypoplasia of the fovea

Hypopigmentation of the fundus

Depigmented fundus

Strabismus

Exotropia

Nystagmus

Nystagmus-induced head nodding

Abnormality of refraction

Myopia

Photophobia

Visual impairment

Reduced visual acuity

Disease(s) Associated with TYR

ocular albinism 1

oculocutaneous albinism type IA

oculocutaneous albinism type IB

Mouse Phenotypes

vision/eye phenotype

choroidal neovascularization

decreased retina photoreceptor cell number

abnormal retina photoreceptor morphology

abnormal eye pigmentation

abnormal iris pigmentation

absent eye pigmentation

ocular albinism

decreased eye pigmentation

variegated eye pigmentation pattern

abnormal aqueous drainage system morphology

abnormal retina morphology

abnormal retina ganglion layer morphology

retina degeneration

abnormal eye physiology

decreased a-wave amplitude

decreased b-wave amplitude

abnormal intraocular pressure

abnormal vision

Availability

Mouse Genotype

Tyr^c-2Btlr/Tyr^c-2Btlr

Tyr^c-2J/Tyr^c-2J

!

Tyr^c-9J/Tyr^c-9J

Tyr^c-10J/Tyr^c-10J

Tyr^c-11J/Tyr^c-11J

Tyr^c-17J/Tyr^c-17J

Tyr^c-20J/Tyr^c-20J

Tyr^c-44H/Tyr^c-44H

Tyr^c-112K/Tyr^c-112K

Tyr^c-Bc2/Tyr^c-Bc2

Tyr^c-Bc3/Tyr^c-Bc3

Tyr^c-Brd/Tyr^c-Brd

Tyr^c-Btlr/Tyr^c-Btlr

Tyr^c-em/Tyr^c-em

Tyr^c-h/Tyr^c-h

Tyr^c-i/Tyr^c-i

*

Tyr^c-p/Tyr^c-p

Tyr^c-Wtsi/Tyr^c-Wtsi

Tyr^cm1OR/Tyr^cm1OR

Tyr^em3J/Tyr^em3J

Tyr^em3Ove/Tyr^em3Ove

Tyr^em5Ove/Tyr^em5Ove

Tyr^em6Ove/Tyr^em6Ove

Tyr^em11Ove/Tyr^em11Ove

Tyr^m3Btlr/Tyr^m3Btlr

Tyr^tm1Arte/Tyr^tm1Arte

Gt(ROSA)26Sor^{tm7.1(CAG-EGFP/RNAi:Tyr)Maoh}/Gt(ROSA)26Sor⁺

Tyr^c-43H/Tyr^c-ch

Tyr^c-Bc/Tyr^c

Tyr^c-h/Tyr^c

Tyr^c/Tyr^c-13J

Tyr^c/Tyr^c-43H

Tyr^c/Tyr^c-44H

Tyr^c/Tyr^c-a

Tyr^c/Tyr^c-ch62H

Tyr^c/Tyr^em3Ove

Tyr^c/Tyr^em5Ove

Tyr^c/Tyr^em8Ove

Tyr^em2Utr/Tyr^em1Utr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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