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Symbol
Name
ID
Sox10
SRY (sex determining region Y)-box 10
MGI:98358
Phenotype annotations related to embryo
Darker colors indicate more annotations
Human Phenotypes
Decreased fetal movement
Disease(s) Associated with SOX10
PCWH syndrome

Mouse Phenotypes
increased vagal neural crest cell apoptosis
abnormal neural crest cell migration
abnormal enteric neural crest cell migration
abnormal melanoblast migration
abnormal vagal neural crest cell migration
abnormal neural crest cell physiology
abnormal frontonasal mesenchyme morphology
abnormal neural crest morphology
abnormal enteric neural crest cell morphology
absent enteric neural crest cell
abnormal melanoblast morphology
Availability Mouse Genotype
Sox10Dom/Sox10Dom
Sox10tm1Weg/Sox10tm1Weg
Sox10tm3(Sox8)Weg/Sox10tm3(Sox8)Weg
Sox10tm4Weg/Sox10tm4Weg
Sox10Dom/Sox10+
Sox10Dom/Sox10+
Tg(DBHn-lacZ)8Rpk/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory