Symbol
Name
ID

Ccn2
cellular communication network factor 2
MGI:95537

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Mouse Phenotypes

abnormal Meckel's cartilage morphology

absent ethmoid bone

short mandible

domed cranium

abnormal nasal cartilage morphology

bowed radius

bowed ulna

bowed fibula

bowed tibia

abnormal appendicular skeleton morphology

abnormal long bone morphology

abnormal long bone hypertrophic chondrocyte zone

increased width of hypertrophic chondrocyte zone

disorganized long bone epiphyseal plate

increased long bone epiphyseal plate size

abnormal sternum morphology

abnormal sternebra morphology

short sternum

abnormal axial skeleton morphology

abnormal thoracic cage morphology

abnormal rib morphology

abnormal vertebral column morphology

abnormal vertebrae morphology

abnormal cervical atlas morphology

abnormal bone structure

decreased bone mineral content

decreased bone mineral density of femur

decreased bone mineral density

abnormal trabecular bone morphology

decreased trabecular bone thickness

abnormal cartilage morphology

abnormal cartilage development

chondrodystrophy

abnormal bone ossification

delayed endochondral bone ossification

abnormal chondrocyte physiology

Availability

Mouse Genotype

Ccn2^tm1Kml/Ccn2^tm1Kml

Ccn2^tm1Mga/Ccn2^tm1Mga

Ccn2^tm1Mga/Ccn2⁺

Ccn2^tm1.1Vlcg/Ccn2^tm1.1Vlcg
Tg(Prrx1-cre)1Cjt/0 (conditional)

Ccn2^tm1Mga/Ccn2^tm1.1Vlcg
Tg(BGLAP-cre)1Clem/0 (conditional)

Ccn2^tm2Mae/Ccn2⁺
Tg(EIIa-cre)C5379Lmgd/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23