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Symbol
Name
ID
Atf4
activating transcription factor 4
MGI:88096
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased insulin secretion
increased insulin secretion
abnormal circulating glucose level
decreased circulating glucose level
increased circulating glucose level
decreased circulating insulin level
increased circulating insulin level
increased circulating alanine transaminase level
increased circulating aspartate transaminase level
abnormal glucose homeostasis
impaired gluconeogenesis
impaired glucose tolerance
improved glucose tolerance
abnormal glycogen homeostasis
increased insulin sensitivity
abnormal calcium ion homeostasis
increased physiological sensitivity to xenobiotic
Availability Mouse Genotype
Atf4tm1Tow/Atf4tm1Tow
Atf4tm1(KOMP)Mbp/Atf4+
Tg(CMV-Atf4)1Kry/0 *
Tg(Col1a1-Atf4)1Kry/0 *
Atf4tm1.1Cmad/Atf4tm1.1Cmad
Tg(Myh11-icre/ERT2)1Soff/?  (conditional)
*
Atf4tm1Kry/Atf4tm1Kry
Tg(Col1a1-cre)1Kry/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory