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Symbol
Name
ID

Piezo1
piezo-type mechanosensitive ion channel component 1
MGI:3603204

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased circulating ferritin concentration	Hemoglobinuria
Disease(s) Associated with PIEZO1	Increased circulating ferritin concentration	Hemoglobinuria
dehydrated hereditary stomatocytosis 1

Mouse Phenotypes		homeostasis/metabolism phenotype	impaired exercise endurance	pericardial effusion	abnormal erythrocyte ion transport	decreased blood osmolality	increased circulating alanine transaminase level	increased circulating transferrin level	decreased circulating haptoglobin level	abnormal calcium ion homeostasis	abnormal enzyme/coenzyme activity
Availability	Mouse Genotype	homeostasis/metabolism phenotype	impaired exercise endurance	pericardial effusion	abnormal erythrocyte ion transport	decreased blood osmolality	increased circulating alanine transaminase level	increased circulating transferrin level	decreased circulating haptoglobin level	abnormal calcium ion homeostasis	abnormal enzyme/coenzyme activity
	Piezo1^em1Bxiao/Piezo1^em1Bxiao	*
	Piezo1^em1Dbee/Piezo1^em1Dbee
	Piezo1^{Gt(RST343)Byg}/Piezo1^{Gt(RST343)Byg}
	Piezo1^{tm1a(KOMP)Wtsi}/Piezo1^{tm1a(KOMP)Wtsi}
	Piezo1^{tm1b(KOMP)Wtsi}/Piezo1⁺
	Piezo1^tm2.1Apat/Piezo1^tm2.1Apat Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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