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Symbol
Name
ID

Dock8
dedicator of cytokinesis 8
MGI:1921396

Phenotype annotations related to cellular

Darker colors indicate more annotations

Human Phenotypes	Increased circulating IgE level	Increased circulating IgG level	Decreased circulating total IgM
Disease(s) Associated with DOCK8	Increased circulating IgE level	Increased circulating IgG level	Decreased circulating total IgM
hyper IgE recurrent infection syndrome 2
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome

Mouse Phenotypes		abnormal cellular extravasation	decreased T cell proliferation
Availability	Mouse Genotype	abnormal cellular extravasation	decreased T cell proliferation
	Dock8^pri/Dock8^pri
	Dock8^tm1Ysfk/Dock8^tm1Ysfk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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