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Symbol
Name
ID

Gdf11
growth differentiation factor 11
MGI:1338027

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Prominent occiput	Micrognathia	Scapular winging	Joint hypermobility	Supernumerary ribs	Pectus excavatum	Six lumbar vertebrae
Disease(s) Associated with GDF11
vertebral hypersegmentation and orofacial anomalies

Mouse Phenotypes

abnormal caudal vertebrae morphology

decreased caudal vertebrae number

abnormal sternocostal joint morphology

abnormal axial skeleton morphology

asymmetric rib joints

abnormal rib morphology

increased rib number

increased thoracic vertebrae number

thoracic vertebral transformation

abnormal vertebral column morphology

abnormal vertebrae morphology

abnormal cervical vertebrae morphology

cervical vertebral transformation

increased lumbar vertebrae number

lumbar vertebral transformation

increased presacral vertebrae number

abnormal sacral vertebrae morphology

absent sacral vertebrae

vertebral transformation

Availability

Mouse Genotype

Gdf11^tm1.1Vlcg/Gdf11^tm1.1Vlcg

Gdf11^tm1Clf/Gdf11^tm1Clf

Gdf11^tm1Sjl/Gdf11^tm1Sjl

Gdf11^tm2.2Sjl/Gdf11^tm2.2Sjl

Gdf11^tm1Sjl/Gdf11⁺

Gdf11^tm2.2Sjl/Gdf11⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23