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Symbol
Name
ID
Gdf11
growth differentiation factor 11
MGI:1338027
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Widow's peak
Prominent occiput
Micrognathia
Midface retrusion
Unilateral cleft lip
Submucous cleft hard palate
Unilateral cleft palate
Anteverted nares
Epicanthus
Disease(s) Associated with GDF11
vertebral hypersegmentation and orofacial anomalies

Mouse Phenotypes
abnormal craniofacial morphology
abnormal facial morphology
abnormal palate morphology
cleft palate
abnormal olfactory epithelium morphology
abnormal olfactory sensory neuron morphology
Availability Mouse Genotype
Gdf11tm1Clf/Gdf11tm1Clf
Gdf11tm1Sjl/Gdf11tm1Sjl
Gdf11tm2b(EUCOMM)Hmgu/Gdf11tm2b(EUCOMM)Hmgu
Gdf11tm1Sjl/Gdf11+
Gdf11tm1.1Vlcg/Gdf11tm1.1Vlcg
Tg(Nanog-cre)#Vlcg/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory