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Symbol
Name
ID
Sucla2
succinate-Coenzyme A ligase, ADP-forming, beta subunit
MGI:1306775
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased activity of mitochondrial respiratory chain
Disease(s) Associated with SUCLA2
mitochondrial DNA depletion syndrome 5

Mouse Phenotypes
cellular phenotype
decreased myocardial fiber mitochondrial DNA content
abnormal mitochondrial morphology
decreased hepatocyte mitochondrial DNA content
decreased mitochondrial DNA content
increased mitochondrial DNA content
abnormal mitochondrial physiology
abnormal oxidative phosphorylation
Availability Mouse Genotype
Sucla2Gt(SAbetageo)1Bhg/Sucla2Gt(SAbetageo)1Bhg
Sucla2Gt(IST10208H1)Tigm/Sucla2+ *
Sucla2Gt(SAbetageo)1Bhg/Sucla2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory