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Symbol
Name
ID
Dnmt3b
DNA methyltransferase 3B
MGI:1261819
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Micrognathia
Sinusitis
Malar flattening
Interphalangeal joint erosions
Swan neck-like deformities of the fingers
Joint swelling
Joint stiffness
Rheumatoid arthritis
Polyarticular arthritis
Digital flexor tenosynovitis
Disease(s) Associated with DNMT3B
immunodeficiency-centromeric instability-facial anomalies syndrome 1
rheumatoid arthritis

Mouse Phenotypes
abnormal cranium morphology
large anterior fontanelle
enlarged frontal bone
wide frontal bone
enlarged interparietal bone
abnormal nasal bone morphology
short nasal bone
abnormal skeleton morphology
thoracic vertebral transformation
lumbar vertebral transformation
Availability Mouse Genotype
Dnmt3btm6Enl/Dnmt3btm6Enl
Dnmt3btm1.1Ics/Dnmt3btm2.1Ics
Dnmt3btm6Enl/Dnmt3btm7Enl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory