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Symbol
Name
ID
Srebf2
sterol regulatory element binding factor 2
MGI:107585
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Decreased level of 1,5 anhydroglucitol in serum
Hyperglycemia
Diabetes mellitus
Type II diabetes mellitus
Insulin resistance
Ketoacidosis
Disease(s) Associated with SREBF2
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
decreased circulating cholesterol level
decreased circulating triglyceride level
abnormal lipid homeostasis
decreased brain cholesterol level
decreased liver cholesterol level
decreased cholesterol level
decreased liver triglyceride level
Availability Mouse Genotype
Srebf2lop13/Srebf2lop13
Srebf2tm1Jdh/Srebf2tm1Jdh
Speer6-ps1Tg(Alb-cre)21Mgn/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory