Symbol
Name
ID

Lepr
leptin receptor
MGI:104993

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Chest pain
Disease(s) Associated with LEPR	Chest pain
coronary artery disease

Mouse Phenotypes

behavior/neurological phenotype

abnormal behavior

abnormal learning/memory/conditioning

abnormal conditioned taste aversion behavior

decreased exploration in new environment

abnormal spatial learning

abnormal spatial reference memory

polydipsia

abnormal eating behavior

abnormal food intake

increased food intake

polyphagia

increased anxiety-related response

impaired righting response

limb grasping

tremors

impaired balance

impaired coordination

trunk curl

abnormal locomotor behavior

abnormal locomotor activation

abnormal locomotor circadian rhythm

abnormal gait

decreased locomotor activity

hyperactivity

pup cannibalization

reduced male mating frequency

Availability

Mouse Genotype

Lepr^db-2J/Lepr^db-2J

Lepr^db-3J/Lepr^db-3J

Lepr^db-5J/Lepr^db-5J

Lepr^db-ad/Lepr^db-ad

Lepr^db-NCSU/Lepr^db-NCSU

Lepr^db-Nokl/Lepr^db-Nokl

Lepr^db/Lepr^db

Lepr^m5Btlr/Lepr^m5Btlr

Lepr^m8Btlr/Lepr^m8Btlr

Lepr^tm1.2Chua/Lepr^tm1.2Chua

Lepr^{tm1b(EUCOMM)Wtsi}/Lepr^{tm1b(EUCOMM)Wtsi}

Lepr^tm1Chua/Lepr^tm1Chua

Lepr^tm1Jke/Lepr^tm1Jke

Lepr^tm1Mgmj/Lepr^tm1Mgmj

Lepr^tm1Yli/Lepr^tm1Yli

Lepr^tm2Yli/Lepr^tm2Yli

Lepr^tm3.1Yli/Lepr^tm3.1Yli

Lepr^tm4Mgmj/Lepr^tm4Mgmj

Lepr^tm5Mgmj/Lepr^tm5Mgmj

Lepr^db/Lepr⁺

Lepr^db/Lepr^db-Nokl

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Tg(Nr5a1-cre)2Lowl/0 (conditional)

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Slc17a6^tm2(cre)Lowl/Slc17a6⁺ (conditional)

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Slc32a1^tm2(cre)Lowl/Slc32a1⁺ (conditional)

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Nts^tm1(cre)Mgmj/Nts⁺ (conditional)

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Prlh^tm1(cre)Smln/Prlh⁺ (conditional)

Lepr^tm1.1Chua/Lepr^tm1.1Chua
Pgr^tm2(cre)Lyd/Pgr⁺ (conditional)

Lepr^tm1Jke/Lepr^tm1Jke
Tg(Pomc1-cre)16Lowl/0 (conditional)

Lepr^tm1.1Chua/Lepr^tm1.2Chua
Nos1^tm1(cre)Mgmj/Nos1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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