|
Symbol Name ID |
Pon1
paraoxonase 1 MGI:103295 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Pedal edema |
Hypercalcemia |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Pleural effusion |
Pulmonary edema |
Abnormality of vitamin B12 metabolism |
Amyloidosis |
| Disease(s) Associated with PON1 | ||||||||||||||||||||
| capillary leak syndrome | ||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | increased circulating LDL cholesterol level |
increased circulating VLDL cholesterol level |
abnormal enzyme/coenzyme activity |
increased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||
| Pon1tm1Lus/Pon1tm1Lus | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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