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Symbol
Name
ID
Cpe
carboxypeptidase E
MGI:101932
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Type II diabetes mellitus
Insulin resistance
Disease(s) Associated with CPE
type 2 diabetes mellitus

Mouse Phenotypes
impaired adaptive thermogenesis
increased fasting circulating glucose level
hypoglycemia
increased circulating glucose level
hyperglycemia
decreased circulating gastrin level
increased circulating insulin level
increased circulating leptin level
decreased circulating adrenocorticotropin level
increased circulating pituitary hormone level
increased circulating growth hormone level
increased circulating triiodothyronine level
increased circulating HDL cholesterol level
increased circulating LDL cholesterol level
increased circulating VLDL cholesterol level
increased circulating cholesterol level
increased circulating triglyceride level
increased circulating calcium level
increased circulating alanine transaminase level
increased circulating alkaline phosphatase level
increased circulating aspartate transaminase level
abnormal energy expenditure
increased respiratory quotient
abnormal glucose homeostasis
impaired glucose tolerance
insulin resistance
abnormal hormone level
increased growth hormone level
increased pituitary hormone level
decreased circulating chloride level
Availability Mouse Genotype
Cpefat/Cpefat
Cpetm1b(EUCOMM)Hmgu/Cpetm1b(EUCOMM)Hmgu
Cpetm1Yplo/Cpetm1Yplo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory