|
Symbol Name ID |
Trps1
transcriptional repressor GATA binding 1 MGI:1927616 |
| Darker colors indicate more annotations |
| Human Phenotypes | Micrognathia |
Ivory epiphyses of the distal phalanges of the hand |
Cone-shaped epiphyses of the middle phalanges of the hand |
Cone-shaped epiphyses of the proximal phalanges of the hand |
Swelling of proximal interphalangeal joints |
Short phalanx of finger |
Short finger |
Clinodactyly |
Brachydactyly |
Avascular necrosis of the capital femoral epiphysis |
Flat capital femoral epiphysis |
Short metatarsal |
Short foot |
Short metacarpal |
Short palm |
Scapular winging |
Accelerated bone age after puberty |
Delayed skeletal maturation |
Coxa magna |
Pectus carinatum |
Hyperlordosis |
Scoliosis |
Osteopenia |
Osteoarthritis |
| Disease(s) Associated with TRPS1 | ||||||||||||||||||||||||
| trichorhinophalangeal syndrome type I | ||||||||||||||||||||||||
| trichorhinophalangeal syndrome type III |
| Mouse Phenotypes | abnormal basicranium morphology |
small basisphenoid bone |
abnormal cranial cartilage development |
absent presphenoid bone |
zygomatic arch hypoplasia |
abnormal dental pulp cavity morphology |
abnormal incisor morphology |
abnormal dentin mineralization |
delayed tooth eruption |
abnormal dentin morphology |
brittle teeth |
abnormal mandibular angle morphology |
mandibular condyloid process hypoplasia |
mandibular coronoid process hypoplasia |
short mandible |
maxillary zygomatic process hypoplasia |
short maxilla |
micrognathia |
vomer bone hypoplasia |
absent tracheal cartilage rings |
decreased length of long bones |
abnormal sternum ossification |
short sternum |
split sternum |
abnormal thoracic cage morphology |
abnormal rib morphology |
increased rib number |
thin ribs |
abnormal thoracic cage shape |
small thoracic cage |
kyphoscoliosis |
scoliosis |
decreased bone mineral density |
abnormal chondrocyte morphology |
abnormal bone ossification |
abnormal endochondral bone ossification |
delayed endochondral bone ossification |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
| Trps1tm1.1Shiv/Trps1tm1.1Shiv | ||||||||||||||||||||||||||||||||||||||
| Trps1tm1Ymur/Trps1tm1Ymur | ||||||||||||||||||||||||||||||||||||||
| Trps1tm1.1Shiv/Trps1+ | ||||||||||||||||||||||||||||||||||||||
| Tg(Tyr,Col1a1-Trps1)1Brle/0 | ||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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