|
Symbol Name ID |
Lepr
leptin receptor MGI:104993 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Anosmia |
Excessive daytime somnolence |
Obstructive sleep apnea |
Snoring |
Focal impaired awareness seizure |
| Disease(s) Associated with LEPR | |||||
| obstructive sleep apnea |
| Mouse Phenotypes | nervous system phenotype |
abnormal axon extension |
decreased somatotroph cell number |
abnormal nervous system morphology |
decreased motor neuron number |
abnormal axon morphology |
abnormal myelin sheath morphology |
abnormal sympathetic nervous system physiology |
abnormal hypothalamus physiology |
abnormal nervous system electrophysiology |
abnormal nerve conduction |
abnormal neuron physiology |
abnormal CNS synaptic transmission |
abnormal inhibitory postsynaptic currents |
reduced long-term potentiation |
absent long-term depression |
abnormal synaptic dopamine release |
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| Availability | Mouse Genotype | |||||||||||||||||
| Leprdb/Leprdb | ||||||||||||||||||
| Leprtm1.2Chua/Leprtm1.2Chua | ||||||||||||||||||
| Leprtm1.1Chua/Leprtm1.1Chua Tg(Nr5a1-cre)2Lowl/0 (conditional) |
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| Leprtm1.1Chua/Leprtm1.1Chua Tg(Syn1-cre)671Jxm/0 (conditional) |
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| Leprtm1.1Chua/Leprtm1.1Chua Tg(Gh1-cre)bKnmn/0 (conditional) |
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| Leprtm1.1Chua/Leprtm1.1Chua Slc17a6tm2(cre)Lowl/Slc17a6+ (conditional) |
* | |||||||||||||||||
| Leprtm1.1Chua/Leprtm1.1Chua Slc32a1tm2(cre)Lowl/Slc32a1+ (conditional) |
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| Leprtm1.1Chua/Leprtm1.1Chua Slc32a1tm2(cre)Lowl/Slc32a1+ Tg(Pomc1-hrGFP)1Lowl/0 (conditional) |
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| Leprtm1.1Chua/Leprtm1.1Chua Tg(Pomc1-cre)16Lowl/0 Tg(Pomc1-hrGFP)1Lowl/0 (conditional) |
* | |||||||||||||||||
| Leprtm1.1Chua/Leprtm1.1Chua Tg(Pomc1-cre)16Lowl/0 (conditional) |
* | |||||||||||||||||
| Agrptm1(cre)Lowl/Agrp+ Leprtm1.1Chua/Leprtm1.1Chua (conditional) |
* | |||||||||||||||||
| Agrptm1(cre)Lowl/Agrp+ Leprtm1.1Chua/Leprtm1.1Chua Tg(Pomc1-hrGFP)1Lowl/0 (conditional) |
* | |||||||||||||||||
| Leprtm1.1Chua/Leprtm1.1Chua Ntstm1(cre)Mgmj/Nts+ (conditional) |
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| Leprtm1.1Chua/Lepr+ Tg(Gh1-cre)bKnmn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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