|
Symbol Name ID |
Prkcq
protein kinase C, theta MGI:97601 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased T cell apoptosis |
increased T cell apoptosis |
decreased T cell proliferation |
decreased splenocyte proliferation |
decreased DN1 thymic pro-T cell number |
abnormal T-helper 1 cell differentiation |
abnormal positive T cell selection |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased NK T cell number |
abnormal effector T cell morphology |
decreased IgG level |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal T-helper 2 physiology |
abnormal T cell activation |
impaired humoral immune response |
decreased interferon-gamma secretion |
decreased interleukin-13 secretion |
decreased interleukin-17 secretion |
decreased interleukin-2 secretion |
decreased interleukin-4 secretion |
decreased interleukin-5 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
abnormal response to infection |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| Prkcqm1Btlr/Prkcqm1Btlr | |||||||||||||||||||||||||||
| Prkcqm2Btlr/Prkcqm2Btlr | |||||||||||||||||||||||||||
| Prkcqtm1.1Bai/Prkcqtm1.1Bai | |||||||||||||||||||||||||||
| Prkcqtm1Litt/Prkcqtm1Litt | * | ||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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