Symbol
Name
ID

B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
MGI:95705

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Splenomegaly	Inflammatory abnormality of the skin
Disease(s) Associated with B4GALT1	Splenomegaly	Inflammatory abnormality of the skin
congenital disorder of glycosylation type IId

Mouse Phenotypes

impaired macrophage chemotaxis

decreased susceptibility to induced colitis

enlarged spleen

increased neutrophil cell number

increased lymphocyte cell number

increased leukocyte cell number

abnormal leukocyte physiology

abnormal neutrophil physiology

impaired neutrophil recruitment

increased IgA level

abnormal IgM level

decreased circulating interleukin-6 level

decreased susceptibility to type IV hypersensitivity reaction

decreased acute inflammation

glomerulonephritis

Availability

Mouse Genotype

B4galt1^tm1Yiw/B4galt1^tm1Yiw

Gt(ROSA)26Sor^{tm1(B4galt1)Clib}/Gt(ROSA)26Sor^{tm1(B4galt1)Clib}
Tg(Nes-cre)Wme/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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