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Symbol
Name
ID 		Ifngr2
interferon gamma receptor 2
MGI:107654
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Immunodeficiency
Recurrent mycobacterial infections
Disease(s) Associated with IFNGR2
immunodeficiency 28

Mouse Phenotypes
immune system phenotype
abnormal diapedesis
insulitis
ovary inflammation
abnormal class switch recombination
abnormal T-helper 1 cell differentiation
abnormal splenic cell ratio
abnormal T-helper 1 physiology
abnormal T-helper 2 physiology
abnormal cytotoxic T cell physiology
decreased susceptibility to type IV hypersensitivity reaction
decreased interferon-gamma secretion
decreased interleukin-4 secretion
decreased tumor necrosis factor secretion
decreased susceptibility to autoimmune diabetes
myositis
increased susceptibility to bacterial infection
increased susceptibility to parasitic infection
Availability Mouse Genotype
Ifngr2tm1Pbro/Ifngr2tm1Pbro
Tg(CD2-Ifngr2)1Pbro/? *
Tg(CD2-Ifngr2)2Pbro/? * ! ! !
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory