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Symbol
Name
ID
Lag3
lymphocyte-activation gene 3
MGI:106588
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
enlarged spleen
increased CD4-positive, alpha-beta T cell number
increased CD8-positive, alpha-beta T cell number
abnormal effector T cell number
increased single-positive T cell number
abnormal NK cell physiology
abnormal T cell physiology
abnormal CD8-positive, alpha-beta T cell physiology
abnormal interleukin level
abnormal tumor necrosis factor level
decreased susceptibility to autoimmune diabetes
Availability Mouse Genotype
Lag3tm1Doi/Lag3tm1Doi
Lag3tm1Daav/Lag3tm1Daav
Tg(Foxp3-EGFP/cre)1cJbs/0  (conditional)
Lag3tm1Daav/Lag3+
Tg(Foxp3-EGFP/cre)1cJbs/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory