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Symbol
Name
ID
Cybb
cytochrome b-245, beta polypeptide
MGI:88574
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormality of neutrophils
Impaired oxidative burst
Granulomatosis
Splenomegaly
Disease(s) Associated with CYBB
chronic granulomatous disease
X-linked chronic granulomatous disease

Mouse Phenotypes
abnormal macrophage chemotaxis
enlarged spleen
increased spleen weight
decreased mean corpuscular volume
increased neutrophil cell number
increased lymphocyte cell number
increased monocyte cell number
abnormal neutrophil physiology
increased IgG level
abnormal macrophage physiology
Availability Mouse Genotype
Cybbtm1Din/Cybbtm1Din
Cybbtm2b(KOMP)Wtsi/Cybbtm2b(KOMP)Wtsi
Cybbtm1Din/Y
Cybbtm1.1Abk/Cybbtm1.1Abk
Lyz2tm1(cre)Ifo/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory