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Symbol
Name
ID
Malt1
MALT1 paracaspase
MGI:2445027
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Decreased lymphocyte proliferation in response to anti-CD3
Absent isohemagglutinin level
Complete or near-complete absence of specific antibody response to tetanus vaccine
Abnormal lymphocyte count
Lymphoma
Disease(s) Associated with MALT1
immunodeficiency 12
non-Hodgkin lymphoma

Mouse Phenotypes
abnormal T cell proliferation
decreased T cell proliferation
abnormal B cell differentiation
abnormal T cell differentiation
abnormal double-negative T cell morphology
absent B-1a cells
abnormal spleen marginal zone morphology
decreased IgG level
decreased IgM level
decreased immunoglobulin level
Availability Mouse Genotype
Malt1m2Btlr/Malt1m2Btlr
Malt1m3Btlr/Malt1m3Btlr
Malt1tm1Mak/Malt1tm1Mak
Malt1tm1Vmd/Malt1tm1Vmd
Malt1m2Btlr/Malt1+
Malt1m3Btlr/Malt1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory