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Symbol
Name
ID

Zeb1
zinc finger E-box binding homeobox 1
MGI:1344313

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

decreased B cell proliferation

abnormal thymus development

small thymus

thymus hypoplasia

decreased thymocyte number

increased thymocyte number

abnormal B cell differentiation

abnormal class switch recombination

abnormal T cell differentiation

decreased double-positive T cell number

decreased neutrophil cell number

decreased germinal center B cell number

decreased B-1 B cell number

decreased B-1a cell number

decreased B-1b cell number

absent marginal zone B cells

decreased NK cell number

abnormal T cell subpopulation ratio

decreased CD8-positive, alpha-beta T cell number

decreased T cell number

increased single-positive T cell number

decreased lymphocyte cell number

decreased leukocyte cell number

small spleen

decreased splenocyte number

decreased IgG1 level

decreased IgG level

decreased IgM level

abnormal memory B cell physiology

Availability

Mouse Genotype

Zeb1^m1Btlr/Zeb1^m1Btlr

Zeb1^tm1Yhi/Zeb1^tm1Yhi

Zeb1^tm2Yhi/Zeb1^tm2Yhi

Zeb1^Tw/Zeb1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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