Symbol
Name
ID

Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
MGI:1336167

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

abnormal thymus morphology

enlarged thymus

enlarged spleen

increased spleen weight

abnormal erythropoiesis

extramedullary hematopoiesis

hemolytic anemia

microcytic anemia

increased erythroid progenitor cell number

increased erythroblast number

abnormal erythrocyte morphology

decreased erythrocyte cell number

decreased hematocrit

increased glycosylated hemoglobin level

decreased hemoglobin content

decreased mean corpuscular hemoglobin

decreased mean corpuscular hemoglobin concentration

decreased mean corpuscular volume

increased red blood cell distribution width

anisocytosis

acanthocytosis

echinocytosis

microcytosis

schistocytosis

stomatocytosis

increased neutrophil cell number

increased mean platelet volume

decreased Ly6C-positive mature NK cell number

increased memory-marker CD4-negative NK T cell number

increased memory-marker gamma-delta T cell number

decreased lymphocyte cell number

abnormal reticulocyte cell number

reticulocytosis

abnormal spleen morphology

increased spleen iron level

increased spleen red pulp amount

decreased erythrocyte osmotic fragility

Availability

Mouse Genotype

Prkab1^em1(IMPC)Bay/Prkab1^em1(IMPC)Bay

Prkab1^em1(IMPC)J/Prkab1^em1(IMPC)J

Prkab1^em2(IMPC)Mbp/Prkab1^em2(IMPC)Mbp

Prkab1^{tm1a(KOMP)Wtsi}/Prkab1^{tm1a(KOMP)Wtsi}

Prkab1^{tm1b(KOMP)Wtsi}/Prkab1^{tm1b(KOMP)Wtsi}

Prkab1^{tm1b(KOMP)Wtsi}/Prkab1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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