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Symbol
Name
ID
Hgf
hepatocyte growth factor
MGI:96079
Phenotype annotations related to hearing/vestibular/ear
Darker colors indicate more annotations
Human Phenotypes
Prelingual sensorineural hearing impairment
Disease(s) Associated with HGF
autosomal recessive nonsyndromic deafness 39

Mouse Phenotypes
increased ear pigmentation
decreased cochlear outer hair cell number
cochlear outer hair cell degeneration
abnormal organ of Corti supporting cell morphology
organ of Corti degeneration
spiral ligament degeneration
abnormal stria vascularis morphology
abnormal strial intermediate cell morphology
thin stria vascularis
decreased endocochlear potential
abnormal distortion product otoacoustic emission
impaired hearing
Availability Mouse Genotype
Hgftm1.1Tbf/Hgftm1.1Tbf
Hgftm1Tbf/Hgftm1Tbf
Tg(Mt1-Hgf)#Lmb/0
Hgftm1Jmw/Hgftm1Jmw
Tg(Pax2-cre)1Akg/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory