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Symbol
Name
ID
Rag2
recombination activating gene 2
MGI:97849
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Reduced antigen-specific T cell proliferation
Decreased lymphocyte proliferation in response to mitogen
Decreased circulating IgA level
Decreased circulating IgG level
Decreased circulating total IgM
Decreased circulating antibody level
Panhypogammaglobulinemia
Disease(s) Associated with RAG2
combined cellular and humoral immune defects with granulomas
severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive

Mouse Phenotypes
decreased T cell proliferation
Availability Mouse Genotype
Rag2tm1Avla/Rag2tm1Avla

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory