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Symbol
Name
ID
Irs1
insulin receptor substrate 1
MGI:99454
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Premature coronary artery atherosclerosis
Hypertension
Sudden cardiac death
Myocardial infarction
Disease(s) Associated with IRS1
coronary artery disease

Mouse Phenotypes
hypertension
increased systemic arterial diastolic blood pressure
increased systemic arterial systolic blood pressure
decreased vasodilation
abnormal vascular wound healing
Availability Mouse Genotype
Irs1tm1Tka/Irs1tm1Tka

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory