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Symbol
Name
ID
Nr3c1
nuclear receptor subfamily 3, group C, member 1
MGI:95824
Phenotype annotations related to cardiovascular system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Premature coronary artery atherosclerosis
Hypertension
Sudden cardiac death
Myocardial infarction
Disease(s) Associated with NR3C1
coronary artery disease

Mouse Phenotypes
cardiovascular system phenotype
increased myocardial fiber size
increased heart weight
enlarged heart
cardiac hypertrophy
increased heart left ventricle weight
dilated heart left ventricle
thick ventricular wall
cardiac fibrosis
poor circulation
decreased cardiac muscle contractility
abnormal heart echocardiography feature
abnormal myocardial fiber physiology
increased mean systemic arterial blood pressure
increased systemic arterial systolic blood pressure
abnormal blood-brain barrier function
pathological neovascularization
congestive heart failure
heart inflammation
Availability Mouse Genotype
Nr3c1tm1Dage/Nr3c1tm1Dage
Nr3c1Gt(ESKN92)Hgs/Nr3c1+
Nr3c1tm1Dage/Nr3c1+
Nr3c1tm2.1Gsc/Nr3c1+
Nr3c1tm1.1Jaci/Nr3c1tm1.1Jaci
Tg(Myh6-cre)2182Mds/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory